• State of Play (2008) (announced) .... Cal McCaffrey
  
• Chad Schmidt (2008) (announced) .... Chad Schmidt/Himself
  
• Dallas Buyer's Club (2008) (announced)
  
• Dirty Tricks (2008) (pre-production)
  
• The Curious Case of Benjamin Button (2008) (filming) .... Benjamin Button
  
• Ocean's Thirteen (2007) (post-production) .... Rusty Ryan
  
• The Assassination of Jesse James by the Coward Robert Ford (2007) (completed) .... Jesse James
  
• San Sebastián 2006: Crónica de Carlos Boyero (2006) (TV) .... Richard
  
• Babel (2006) .... Richard
  Mr. & Mrs. Smith (2005) .... John Smith
  Ocean's Twelve (2004) .... Rusty Ryan
  
• Troy (2004) .... Achilles
  
• "King of the Hill" .... Patch Boomhauer (1 episode, 2003)
  
• Sinbad: Legend of the Seven Seas (2003) (voice) .... Sinbad
  
• Confessions of a Dangerous Mind (2002) .... Brad, Bachelor #1
  
• Full Frontal (2002) .... Brad/Himself
  Ocean's Eleven (2001) .... Rusty Ryan
  
• "Friends" .... Will Colbert (1 episode, 2001)
  
• Spy Game (2001) .... Tom Bishop
  
• The Mexican (2001) .... Jerry Welbach
  
• Snatch. (2000) .... Mickey O'Neil
  Fight Club (1999) .... Tyler Durden
  Meet Joe Black (1998) .... Joe Black
  
• The Dark Side of the Sun (1997) .... Rick
  
• Seven Years in Tibet (1997) .... Heinrich Harrer
  
• The Devil's Own (1997) .... Rory Devaney/Francis Austin McGuire
  
• Sleepers (1996) .... Michael Sullivan
  
• Twelve Monkeys (1995) .... Jeffrey Goines
  
• Se7en (1995) .... Detective David Mills
  
• Legends of the Fall (1994) .... Tristan Ludlow
  
• Interview with the Vampire: The Vampire Chronicles (1994) .... Louis de Pointe du Lac
  
• The Favor (1994) .... Elliott Fowler
  
• True Romance (1993) .... Floyd
  
• Kalifornia (1993) .... Early Grayce
  
• A River Runs Through It (1992) .... Paul Maclean
  
• "Tales from the Crypt" .... Billy (1 episode, 1992)
  
• Cool World (1992) .... Detective Frank Harris
  
• Contact (1992) .... Cox
  
• Johnny Suede (1991) .... Johnny Suede
  
• Thelma & Louise (1991) .... J.D.
  
• Across the Tracks (1991) .... Joe Maloney
  
• Two-Fisted Tales (1991) (TV) .... Billy (segment "King of the Road")
  
• "Glory Days" (1990) TV Series .... Walker Lovejoy (unknown episodes, 1990)
  
• Too Young to Die? (1990) (TV) .... Billy Canton
  
• The Image (1990) (TV) .... Steve Black
  
• "thirtysomething" .... Bernard (1 episode, 1989)
  
• Cutting Class (1989) .... Dwight Ingalls
  
• Happy Together (1989/I) .... Brian
  
• "Growing Pains" .... Jeff ... (2 episodes, 1987-1989)
  
• "Freddy's Nightmares" .... Rick Austin (1 episode, 1989)
  
• "Head of the Class" .... Chuck (1 episode, 1989)
  
• A Stoning in Fulham County (1988) (TV) .... Theodore 'Teddy' Johnson
  
• "21 Jump Street" .... Peter (1 episode, 1988)
  
• "Dallas" .... Randy (3 episodes, 1987-1988)
  
• "Another World" (1964) TV Series .... Chris (unknown episodes, 1987)
  
• Less Than Zero (1987) (uncredited) .... Partygoer/Preppie Kid At Fight
  
• No Man's Land (1987) (uncredited) .... Waiter